Analysis of Symptoms (Endocrinology)

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Analysis of symptoms in Endocrinology

Referring to how you analysis a symptom in the last post here are the common clinical features in endocrine disease.

Ask for:

1. Weight Gain - Hypothyroidism, PCOS, Cushing Syndrome
2. Weight Loss - Hyperthyroidism, DM, Adrenal Insufficiency
3. Short stature - Constitutional, non-endoncrine systemic disease e.g. coeliac disease , GH deficiency
4. Delayed Puberty - Constitutional, non-endocrine systemic disease e.g. hypothyroidism, hypopituitarism, primary gonadal failure
5. Menstrual disturbance - PCOS, hyperprolactinaemia, thyroid  disfunction
6. Diffuse neck swelling - Simple goitre, Graves' disease, Hashimoto's thyroiditis
7. Excessive thirst - DM or Insipidus, hyperparathyroidism, Conn's syndrome
8. Hirsutism - Idiopathic, PCOS, Cushing's Syndrome , congenital adrenal hyperplasia
9. 'Funny Turns' -  Hypoglycaemia, phaeochromocytoma, neuroendocrine tumour
10. Sweating -  Hyperthyroidism, hypogonadism, acromegaly , phaeochrmocytoma
11. Resistant Hypertension - Conn's syndrome, Cushing's , phaeochromocytoma ,acromegaly , renal artery stenosis
12. Erectile Dysfunction -  Primary/2ndry hypogonadism, DM, Non-endocrine systemic disease
13. Muscle Weakness - Cushing's syndrome, hyperthyroidism, hyperparathyroidism, osteomalacia
14. Bone fragility and fractures - Cushing's syndrome , hypogonadism, hyperthyroidism
15. Altered facial appearance - Hypothyroidism, Cushing's Syndrome, acromegaly, PCOS

These are few common symptoms to be analysis in an endocrine case :)

References : Macleod's Clinical Examination 12th Edition